Many people with Alzheimer's disease develop symptoms including delusions, agitation, aggressive behavior, or hallucinations. These symptoms add to the many difficulties of living with Alzheimer's disease.

The CATIE Alzheimer's Disease Study aims to find out the most effective medication treatments for these symptoms, and to improve the quality of life of people with Alzheimer's disease, their families, and caregivers.

CATIE-AD Update and Results Rollout

The last CATIE-AD patient completed the trial in October. Over the last few months, we have been working assiduously to lock the database and check the analysis programming.

CATIE-AD is a trial that will provide layers of results. The complex outcomes will depend not only on randomized treatment assignment but the interactions of the clinical sites with the patients and caregivers. The main goals are to generate hypotheses about effectiveness and other issues with antipsychotic use that might undergo future testing. Dissemination of outcomes from CATIE-AD will be rolled out over the next 8 months at several meetings.

These meetings are:

• American Association of Geriatric Psychiatry, San Diego, March 6, 2005

• American Geriatrics Society Annual Scientific Meeting , Orlando, May 13, 2005

• American Psychiatric Association Annual Meeting – Atlanta, May 25, 2005

• International Psychogeriatric Association 12th Annual Congress – Stockholm, September 20-24, 2005

As these results are presented, other analyses will be undertaken, assessing aspects of effectiveness, quality of life, and healthcare utilization.

Alzheimer's Disease Study